患者男,53岁,因进行性四肢无力4个月于1982年5月30日入院。患者于同年1月起左下肢无力,以后相继发生右下肢,双上肢对称性无力,易疲劳,无四肢麻木感,无排尿障碍。入院时一般体检无异常,神经系:四肢近端肌肉轻度萎缩,双上肢近端肌力Ⅲ°,远端Ⅳ°,双下肢肌力Ⅲ°,肌张力减退,腱反 The patient, male, 53 years old, was admitted to hospital on May 30, 1982 due to progressive limb weakness for 4 months. Patients in the same year in January from the left lower limb weakness, have occurred after the right lower limb, upper limb symmetry weakness, fatigue, no limb numbness, no dysuria. Normal physical examination on admission was normal, nervous system: mild muscle contraction proximal limbs, proximal upper limb muscle III °, distal Ⅳ °, lower limb muscle strength Ⅲ °, hypotonia, tendon