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目的：探讨运动对缺血性心脏病（ＩＨＤ）ＱＴ离散度的影响及β受体阻滞剂的干预作用。方法：观察２７例ＩＨＤ（ＩＨＤ组），２４例接受β受体阻滞剂治疗的ＩＨＤ（ＩＨＤ－β组）和１４例正常人（正常组）静息和平板运动高峰时ＱＴ间期及其相关参数。结果：静息和运动高峰时ＩＨＤ和ＩＨＤ－β组ＱＴ间期较正常组显著延长，但心率校正后差异无显著性。ＩＨＤ与正常组比较，静息时ＱＴｄ，ＱＴｃｄ，运动高峰时ＱＴｄ，ＱＴｃｄ均显著增加。ＩＨＤ－β组与ＩＨＤ组比较，静息时ＱＴｄ，ＱＴｃｄ显著延长，但运动高峰时差异无显著性。而ＩＨＤ－β组和正常组比较，仅运动时ＱＴｄ，ＱＴｃｄ显著增加，静息时ＱＴｄ，ＱＴｃｄ差异无显著性。ＱＴｄ，ＱＴｃｄ变化率ＩＨＤ组显著高于ＩＨＤ－β组和正常组。结论：ＩＨＤ患者运动高峰时ＱＴｄ及其ＱＴｄ，ＱＴｃｄ变化率增加，β受体阻滞剂降低运动诱发的ＱＴｄ，ＱＴｃｄ升高，缩小运动高峰时心肌缺血复极的离散程度。
Objective: To investigate the effect of exercise on QT dispersion in ischemic heart disease (IHD) and the effect of β-blocker. Methods: The QT interval and the QT interval at resting and platelet movement in 27 patients with IHD (IHD group), 24 patients with IHD (β-blocker) and 14 normal subjects (normal group) Related parameters. Results: The QT interval of IHD and IHD-β group at resting and exercise peak was significantly longer than that of the normal group, but there was no significant difference after correction of heart rate. IHD compared with the normal group, resting QTd, QTcd, peak exercise QTd, QTcd were significantly increased. IHD-β group compared with IHD group, resting QTd, QTcd significantly prolonged, but the difference was not significant at the peak of exercise. However, compared with the normal group, the QTd and QTcd of the IHD-β group were significantly increased only during exercise, and there was no significant difference between the QTd and QTcd groups at rest. QTd, QTcd rate of change IHD group was significantly higher than the IHD-β group and the normal group. Conclusion: The QTd, QTd and QTcd changes of patients with IHD at peak exercise time are increased. Beta blockers reduce QTd and QTcd induced by exercise, and reduce the dispersion of repolarization of myocardial ischemia at peak exercise time.