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血浆Ｄ－二聚体（Ｄ－ｄｉｍｅｒ）作为交联纤维蛋白的特异性降解产物，其浓度升高提示体内纤维蛋白溶解活性增强，是体内纤维蛋白溶解亢进的分子标志物之一。为进一步探讨其临床应用价值，本文测定７０例恶性肿瘤患者血浆Ｄ－二聚体水平，了解其在肿瘤诊治方面的临床意义。１
As a specific degradation product of cross-linked fibrin, plasma D-dimer (D-dimer) is one of the molecular markers for the increase of fibrinolytic activity in vivo, indicating that the increased concentration of D-dimer indicates an increase in fibrinolytic activity in vivo. In order to further explore its clinical value, we measured the level of plasma D-dimer in 70 patients with malignant tumor and found out its clinical significance in the diagnosis and treatment of cancer. 1