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卵巢恶性Brenner氏瘤(MBT)和移行细胞癌(TCC)是两类少见的卵巢原发癌.组织形态类似泌尿道的移行上皮,两者以TCC不含典型的Brenner瘤成分来划分,支持这一观点的理由是TCC中找不见Brenner瘤中所常见的间质钙化,TCC较MBT更具浸润性.本文通过对3例MBT与9例TCC临床及病理资料比较,结合文献复习对TCC进一步探讨,认为MBT应视为由良性Brenner瘤发展而来.而TCC应视为体腔上皮直接化生发展而来.将TCC进一步分为纯型,占优势型,灶性型及对TCC成分划分为乳头状型和MBT样型.进一步研究发现,乳头状型较MBT样型临床分期高,但不管是纯型,占优势型,乳头状型还是MBT样型,化疗反应都有效,灶性型预后可能与其中占优势的其他非TCC成分有关.
Malignant Brenner’s tumor of the ovary (BT) and transitional cell carcinoma (TCC) are two rare types of primary ovarian cancer with a histological morphology similar to that of the urinary tract, both classified as having a TCC free of typical Brenner tumor components One reason is that TCC can not find the common Brenner tumor of interstitial calcification, TCC more invasive than MBT.Through the 3 cases of MBT and 9 cases of TCC clinical and pathological data, combined with the literature review of TCC to further explore , That MBT should be considered as the development of benign Brenner tumors come from .TCC should be considered as the direct development of body cavity epithelial metaplasia.TCC will be further divided into pure, predominant, focal type and the TCC component is divided into nipple Type and MBT type.Further study found that the clinical manifestations of papillary type MBT higher than the clinical stage, but whether pure, dominant, papillary or MBT-like model, the chemotherapy response are effective, focal prognosis may be Related to the other non-TCC components in which it is dominant.