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活性炭有吸附作用,以前认为口服时只能吸附胃肠中未被吸收的药物。80年代以来经临床研究证明,口服或静注若干药物后再口服活性炭可使药物t_(1/2)明显缩短。血液中药物能渗入胃肠中,而活性炭吸附药物加速了药物由血液渗入胃肠中的速度,使血液中药物浓度逐渐下降。临床经验证明单用活性炭救治急性药物中毒效果不如活性炭与泻剂合用。给予活性炭、泻剂并碱化尿效果亦佳。应用适当剂量泻剂不会诱发体内电解质失衡。活性炭用量不宜过大,活性炭应用频率不是影响疗效的主要因素。
Activated carbon has adsorption, previously considered only oral absorption of gastrointestinal unabsorbed drugs. Since the 1980s, clinical studies have shown that oral or intravenous injection of certain drugs after oral administration of activated carbon can make the drug t_ (1/2) significantly shortened. Blood drugs can penetrate the gastrointestinal, and activated carbon adsorption drugs to speed up the drug from the blood infiltration into the gastrointestinal tract, the blood drug concentration decreased. Clinical experience has shown that single activated carbon treatment of acute drug poisoning is not as effective as activated carbon and laxatives. Give activated carbon, cathartic and alkalized urine effect is also good. Applying an appropriate dose of laxatives does not induce an imbalance in the body’s electrolytes. The amount of activated carbon should not be too large, the frequency of activated carbon is not the main factor affecting the efficacy.