恶性淋巴瘤同时合并非淋巴细胞性白血病极为少见.我们最近收治1例为文献所述中年龄最小者.报告如下。病历摘要患者,男性,16岁。因全身浅表淋巴结肿大半月于1989年9月23日入院。半月前患者“感冒”后发现全身浅表淋巴结肿大,伴乏力、肌肉酸痛。无畏寒发热、咳嗽咽痛及鼻衄龈血。既往体健,无放射线和特殊毒物或药物接触及服用史。体检:巩膜无黄染、皮肤无紫癜瘀斑。两侧枕后,颌下、颈部、腋下及腹股沟均触及蚕豆大小密集成串的淋巴结,质韧、不粘连、无压痛。胸骨无叩痛,心肺无异常。腹软,肝脾肋下未触及。实验室检查:RBC3.66×10~(12)/L,Hb91g/L,WBC1.5×10~9/L,分类N43%,L48%,M2% 原始粒细胞4%早幼粒细胞3%,血小板24×10~9/L。骨髓象粒系增生极度旺盛,原始粒细胞(Ⅰ型+Ⅱ型)83%,且呈病理性改变,部分胞浆内见Auer 小体,POX,SB 强阳性,PAS 阴性。腋下淋巴结活检病理 Malignant lymphoma combined with non-lymphocytic leukemia is extremely rare, and we recently admitted a case of the youngest described in the literature, the report is as follows. Patient summary, male, 16 years old. Due to systemic superficial lymph nodes half a month on September 23, 1989 admission. Half a month before the patient “cold” and found that systemic superficial lymph nodes, with fatigue, muscle soreness. Fearless cold fever, cough, sore throat and epistaxis gingival blood. Previous physical health, no radiation and special toxic or drug contact and taking history. Physical examination: Sclera no yellow dye, no purpura ecchymosis skin. Pillow on both sides, the submandibular, neck, armpits and groin are touching the string of broad beans in clusters of lymph nodes, quality and toughness, no adhesion, no tenderness. No sternal chest pain, no abnormal heart and lung. Abdominal soft, liver and spleen ribs did not touch. Laboratory examination: RBC3.66 × 10-12 / L, Hb91g / L, WBC1.5 × 10-9 / L, classification N43%, L48%, M2% of the original granulocyte 4% of the promyelocytic 3% , Platelets 24 × 10 ~ 9 / L. Myeloid hyperplasia is extremely exuberant, 83% of the original granulocytes (type Ⅰ + Ⅱ), and pathological changes, some Auer bodies in the cytoplasm, POX, SB strongly positive, PAS negative. Armpit lymph node biopsy pathology