论文部分内容阅读
很多研究者认为,逐步增加变应原剂量进行长期特异性脱敏所以有效,是由于它能够刺激封闭性抗体合成的缘故.已证实这种刺激可暂时激活反应性抗体的形成过程,但随后这种抗体的产生就被选择性抑制.后者对防止患者在与相应变应原接触时发生变态反应有决定性意义.以上抗体产生顺序与制剂开始使用的剂量小(对IgE、IgG抗体的合成都合适),而后逐步增加到较大剂量(对IgG类抗体的产生合适)有关.因此在治疗过程中到使用大剂量时,可见封闭性抗体含量进一步增加,而IgE抗体却被抑制.
Many researchers believe that increasing the allergen dose for long-term specific desensitization is effective because it stimulates the synthesis of the blocking antibody, which has been shown to temporarily activate the formation of reactive antibodies, but then The production of antibodies is selectively inhibited and the latter is of decisive importance in preventing the patient from developing an allergic reaction to the corresponding allergen.The order of production of the above antibodies is small compared to the dose at the beginning of the preparation (for both IgE and IgG antibodies ), And then gradually increased to a larger dose (for the production of IgG antibodies appropriate) Therefore, in the course of treatment to the use of high doses, we can see a further increase in the content of blocking antibodies, while IgE antibodies were inhibited.