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答:C反应蛋白(CRP)是在急性炎症时出现的一种非特异性急性期蛋白,一直用来检查和预测各种传染性、感染性和坏死性过程的结局,并评估这些过程的治疗效果。目前发现CRP可以预测健康个体将来发生冠脉事件以及估计急性冠脉综合征(ACS)患者的预后。CRP作为炎症标志物被认为是心血管事件危险最强有力的预测因子之一,已引起国内外学者极大兴趣和广泛关注。主要原因在于临床实验室采用了高敏感或超敏感(检测低限为0.005～0.10 mg/L不等)的检测技术,能很准确地测定低浓度CRP(如0.15～10 mg/L)。用这些方法所测定的CRP常称为超敏CRP(hs-CRP)。 hs-CRP测定的临床意义有:(1)hs-CRP可作为ACS的预后指标:hs-CRP轻度升高是冠状事件、卒中及周围血管病
A: C-reactive protein (CRP) is a nonspecific acute phase protein found in acute inflammation that has been used to examine and predict the outcome of various infectious, infectious, and necrotic processes and to assess the efficacy of these procedures . It has been found that CRP can predict future coronary events in healthy individuals and prognosis in patients with acute coronary syndrome (ACS). CRP, as a marker of inflammation, is considered as one of the most powerful predictors of cardiovascular risk and has drawn great interest and widespread attention from scholars at home and abroad. The main reason is that clinical laboratories use highly sensitive or hypersensitive (detection limits ranging from 0.005 to 0.10 mg / L) to accurately measure low-level CRP (eg, 0.15 to 10 mg / L). CRP measured by these methods is often called hypersensitive CRP (hs-CRP). The clinical significance of hs-CRP determination: (1) hs-CRP can be used as a prognostic indicator of ACS: mild hs-CRP is a coronary event, stroke and peripheral vascular disease