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目的通过回顾性病例分析研究总结交感应激性遗传性心律失常的临床特征。方法 54例交感应激后诱发心律失常的遗传性心律失常患者进行询问病史,全面体格检查以及心电图、超声心动图、平板运动试验等严格检出和控制入选研究对象,并进行统计分析。结果研究对象平均发病年龄为18.4±14.5岁,有晕厥或猝死家族史者46.3%;以晕厥为首发症状者占94.4%,其次为心悸42.6%和头晕33.3%;诱发因素中运动和劳累占50.0%,精神因素占50.0%,病理因素占11.1%。结论交感应激时CPVT和ARVC患者相对于LQTs患者,恶性室性心律失常事件发生率高并且呈多样化。
Objective To summarize the clinical characteristics of sympathetic stress-induced arrhythmia by retrospective case analysis. Methods Fifty-four patients with hereditary arrhythmia induced by sympathetic stress were asked about their medical history, general physical examination, electrocardiogram, echocardiography and treadmill exercise test, and their data were analyzed statistically. Results The average age of onset of the study was 18.4 ± 14.5 years, 46.3% with a family history of syncope or sudden death, 94.4% with syncope as the first symptom, followed by 42.6% with palpitation and 33.3% with dizziness, 50.0 with exercise and fatigue %, Mental factors accounted for 50.0%, pathological factors accounted for 11.1%. Conclusions Sympathetic stress in patients with CPVT and ARVC relative to LQTs patients, the incidence of malignant ventricular arrhythmia is high and diversified.