目的研究新生儿外周动静脉同步换血疗法。方法100例新生儿重症高胆红素血症分二组。50例治疗组(换血组),50例对照组(光疗+药物),观察两组的治疗效果。结果治疗组疗效优于对照组。结论新生儿外周动静脉同步换血,操作简单、安全、无明显并发症,可迅速清除血中游离的间接胆红素、抗体、致敏红细胞,纠正贫血,阻止胆红素脑病的发生。临床疗效满意,值得推广。 Objective To study neonatal peripheral arteriovenous exchange transfusion therapy. Methods 100 neonates with severe hyperbilirubinemia were divided into two groups. 50 cases of treatment group (transfusion group), 50 cases of control group (phototherapy + drug), the two groups were observed the therapeutic effect. Results The treatment group than the control group. Conclusion Neonatal peripheral arterial and venous exchange of blood simultaneously, simple, safe, no obvious complications, the rapid removal of blood free indirect bilirubin, antibodies, sensitized erythrocytes, correct anemia, prevent the occurrence of bilirubin encephalopathy. Satisfactory clinical results, it is worth promoting.