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目的 了解替加色罗对大鼠内脏感觉功能的影响。方法 清洁级SD大鼠 ,在日龄 8～ 2 1天时每天进行结肠直肠扩张 (CRD组 ) ,应用血管成形术气囊经直肠插至降结肠 ,注入 0 3mL水扩张气囊 (压力约 6 0mmHg) ,1分钟后抽出并撤出气囊。 30分钟后重复一次。对照组仅用导管在肛门周围
Objective To investigate the effect of tegaserod on visceral function in rats. Methods SD SD rats were treated with colorectal distension (CRD) every day of 8-21 days. Angioplasty balloon was inserted into the descending colon through the rectum and infused 0 3 mL water balloon (pressure about 60 mmHg) Remove and evacuate the airbag after 1 minute. Repeat after 30 minutes. The control group only catheter around the anus