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Fluosol是一种新合成的载氧药物,英国近期将用于临床。其主要作用是在进行冠状血管形成术时降低病人的心肌局部缺血。 Fluosol是一种含有两个全氟化合物的乳液,能够转移和释放氧气,它在输液袋的高压下载氧,在人体细胞的低压下释氧。自1977年Fluosol在冠状血管形成术中应用首次获得成功以来,已日益增多地应用于冠状动脉狭窄的治疗,该手术是用一个带气球阀的导管,通向狭窄部分,然后将气球充气,这样就可将动脉粥样化斑块压扁、破裂,
Fluosol is a newly synthesized oxygen carrier and will be used clinically in the UK in the near future. Its primary role is to reduce myocardial ischemia in patients undergoing coronary angioplasty. Fluosol is an emulsion containing two perfluorinated compounds that transports and releases oxygen. It delivers oxygen under the high pressure of the infusion bag and releases oxygen under the low pressure of human cells. Since its first successful use in coronary angioplasty in 1977, Fluosol has been increasingly used for the treatment of coronary artery stenosis by using a catheter with a balloon valve leading to the stenosis and then inflating the balloon so that Atherosclerotic plaque can be crushed, ruptured,