在正常妊娠的孕妇,由于铜兰蛋白合成增加,血清铜浓度几乎成倍增加;其肝中铜含量亦增加。这些机制虽不十分清楚,但与胎盘产生的激素有关系。据报导,早产儿摄入缺铜乳汁将发生嗜中性粒细胞减少症、贫血和坏血性骨改变。在这些婴儿,生长受影响,血清铜和铜兰蛋白浓度明显降低。 In normal pregnant women, the serum copper concentration is almost doubled due to the increased synthesis of cerulein, and the copper content in the liver is also increased. Although these mechanisms are not very clear, but the hormone associated with the placenta. It has been reported that neutropenia, anemia, and craniocerebral changes occur in premature infants who lack copper-deficient milk. In these infants, growth is affected and serum copper and cerulein concentrations are significantly reduced.