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目的观察西沙必利对老年慢性功能性便秘患者的治疗作用及安全性。方法选择 45例经内镜检查证实肠道无器质性病变的老年慢性功能性便秘患者 ,采用口服西沙必利 5 mg,每日 3次 ,有效者继续维持治疗 1个月 ;无效者 ,用强泻药排通大便后 ,再口服西沙必利 5 mg,每日 3次 ,疗程 1个月。结果西沙必利治疗老年慢性功能性便秘 1周及 1个月的显效率分别为 3 3 .3 %、76.2 % ;总有效率分别为 75 .6%、10 0 %。其中 3例发生腹痛或腹痛加重停止使用 ,其余 42例均未见任何副作用。结论西沙必利治疗老年慢性功能性便秘是有效和安全的 ,尤其对便形正常的便秘患者更为理想
Objective To observe the therapeutic effect and safety of cisapride on senile patients with chronic functional constipation. Methods A total of 45 elderly patients with chronic functional constipation who had no pathological organic disease confirmed by endoscopy were enrolled in this study. Oral cisapride (5 mg) was administered orally 3 times a day for 6 months. Strong laxative row after stool, and then oral cisapride 5 mg, 3 times a day for 1 month. Results The effective rates of cisapride in the treatment of senile chronic functional constipation were 33.3% and 76.2% at 1 week and 1 month respectively. The total effective rates were 75.6% and 100% respectively. Among them, 3 cases had abdominal pain or aggravated abdominal pain, and the other 42 cases had no side effects. Conclusion Cisapride is effective and safe in the treatment of senile chronic functional constipation, especially for normal constipation patients