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目的:了解甘精胰岛素与中效胰岛素对血糖控制不佳的2型DM患者的疗效并进行对比.方法现将我院2008年2月~2014年6月收治的血糖控制不佳的2型糖尿病的患者80例列为研究对象.实验组40名DM患者均在每日睡前予以皮下注射甘精胰岛素,剂量为10IU;对照组40名患者均在每日睡前予以皮下注射诺和灵N,剂量为8 IU.以GLU、PPG、HbA1c值、平均每日标准差和平均每日极差值为评价指标,进行对比分析.结果在研究结束后,实验组的的GLU、PPG和HbA1c值所反映的患者水平情况均优于对照组;标准差和极差值所反映出实验组患者血糖波动幅度小于对照组;实验组发生低血糖发生率显著少于对照组,两组比较具有统计意义(P<0.05).结论甘精胰岛素对血糖控制不佳的2型DM患者的疗效显著优于中效胰岛素. “,”Objective To investigate the efficacy of insulin glargine and intermediate-acting insulin for glycemic control in patients with type 2 DM and compared.Methods Now in our hospital from February 2008 to June 2014 admitted glycemic control in patients with type 2 diabetes, 80 cases classiifed as poor study. 40 DM patients in the experimental group were to be on a daily subcutaneous injection of insulin glargine at bedtime dose of 10IU; the control group 40 patients received subcutaneous injection of Novolin N at bedtime daily dose of 8IU. In GLU, PPG, HbA1c value, standard deviation and the average daily value of average daily poor evaluation were analyzed.Results After the end of the study, patient-level case GLU, PPG and HbA1c values as relfected in the experimental group were better than the control group; standard deviation and range values relfect the lfuctuations of blood glucose in patients in the experimental group than the control group; experimental group the incidence of hypoglycemia was significantly less than the control group, the difference was statistically significant (P〈0.05). Conclusions Insulin glargine on glycemic control poor efifcacy in patients with type 2 DM was signiifcantly better than the intermediate-acting insulin.