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意大利Ottobrelli A等人在意大利和比利时研究了27名乙型肝炎表面抗原携带者因丁型肝炎病毒(HDV)引起的肝硬变末期而进行了肝脏移植手术的情况。其中22人发生了HDV感染的复发。2人死于HDV和乙型肝炎病毒(HBV)的混合再活化过程。4人死于原因不明的HDV感染,但没有HBV再活化的象征。5人肝移植后(18%)清除了HBV和HDV,而且在平均随访29个月中,没有显示肝炎的症状。很多存活者早期就出现了HDV感染的复发,但没有HBV的再活化现象。11名患者,HDV和HBV都出现复发。而只有HDV但没有HBV复发的5名患者在12~33个月期间,组织学肝炎检查阴性。进行肝移植的HDV患者总的
Italy Ottobrelli A et al studied in Italy and Belgium 27 patients with hepatitis B surface antigen due to hepatitis D virus (HDV) -related cirrhosis of the liver transplant. Of the 22 patients, a recurrence of HDV infection occurred. Two died of mixed reactivation of HDV and hepatitis B virus (HBV). Four people died of unexplained HDV infection, but no sign of HBV reactivation. HBV and HDV were cleared after 5 human liver transplants (18%) and no symptoms of hepatitis were observed during the mean follow-up of 29 months. Many survivors have had early recurrence of HDV infection but no reactivation of HBV. Eleven patients experienced relapse between HDV and HBV. Five patients with HDV but no HBV relapse had histologic hepatitis negative within 12-33 months. HDV patients undergoing liver transplantation total