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目的了解妊娠期细小病毒B19感染情况,为制订实施更为科学有效的产前筛查方法提供基础数据。方法选取2016年1月至5月在中国人民解放军第二0二医院进行产检的志愿者妇女455例,其中育龄妇女组69例,正常孕妇组223例,胎停孕妇组74例,胎儿异常流产或引产组89例。将各组资料与国内外相关研究进行比较。收集各组血清标本进行B19 Ig G、Ig M抗体测定。结果与育龄妇女组比较,其余各组B19 Ig G、Ig M阳性率差异无统计学意义(P>0.05)。本地区育龄妇女B19 Ig G、Ig M阳性率均低于国内外相关研究结果(P<0.05)。结论建议对高危人群在孕前评估对B19的免疫力,对易感人群在孕期进行B19病毒筛查。
Objective To understand the status of parvovirus B19 infection in pregnancy and provide the basic data for the development of a more scientific and effective prenatal screening method. Methods A total of 455 volunteers from January 2016 to May 2016 at the Chinese People’s Liberation Army No.202 Hospital were selected, of whom 69 were women of childbearing age, 223 were normal pregnant women, 74 were pregnant women with fetal abortion, and the abortion was abnormal Or induced abortion group of 89 cases. Compare each group of data with relevant research at home and abroad. Serum samples of each group were collected for B19 Ig G, Ig M antibody determination. Results Compared with women of childbearing age, the positive rates of B19 Ig G and Ig M in other groups were not significantly different (P> 0.05). The positive rates of B19 Ig G and Ig M in women of childbearing age in this area were lower than those of related research at home and abroad (P <0.05). Conclusion It is suggested that the immunity to B19 be evaluated before pregnancy in high-risk groups and the B19 virus should be screened in pregnant women during pregnancy.