大量数据显示面粉中强化叶酸能有效预防出生缺陷的发生并降低其危害性。影响叶酸强化面粉对出生缺陷作用的因素可能包括:种族差异、孕妇年龄及受教育程度、围产期的医疗质量水平、叶酸强化的剂量等。面粉中强化叶酸是预防出生缺陷安全有效的措施,能够最大程度地保障妇女在孕期摄入足够的叶酸以预防和控制新生儿出生缺陷的发生。 A large number of data show that the strengthening of folic acid in flour can effectively prevent the occurrence of birth defects and reduce its harmfulness. Factors that may affect the effect of folate-fortified flour on birth defects may include: race differences, age and education of pregnant women, quality of care during perinatal period, doses of folic acid fortification, and the like. Intensified folic acid in flour is a safe and effective measure to prevent birth defects, which can ensure women’s intake of enough folic acid during pregnancy to prevent and control the birth defects of newborns.