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脑梗死是脑部血液循环障碍而缺血、缺氧所致的局限性脑组织坏死,诊治重在根据发病时间、临床表现、病因及病理进行分型分期,综合全身状态,实施个体化治疗。其中,在急性期采取积极、合理的治疗措施尤为重要。在众多评价不一的治疗措施中,脑保护治疗尤为人们关注,因为理论上其可延长脑细胞耐受缺血的时间,也可提高脑细胞在血供改善(尤其是溶栓复流)之后的生存能力。目前,脑保护剂的作用更是诸多脑保护治疗措施中的一个充满困惑和争议的话题,现就此从以下三个方面谈些管见: 1 脑保护治疗的病理生理基础众所周知,梗死组织周边存在的缺血半暗带是脑梗死现代治疗的基础,若能及时恢复血流和改善
Cerebral infarction is a result of ischemia and hypoxia caused by cerebral blood circulation disorders. The most important diagnosis and treatment is based on the time of onset, clinical manifestations, etiology and pathology. Among them, in the acute phase to take positive and reasonable treatment is particularly important. Among many treatments of varying severity, brain protection therapy is of particular concern as it theoretically increases the time it takes a brain cell to tolerate ischemia and also increases the number of brain cells that can improve after blood supply is improved (especially thrombolysis) Survivability. Currently, the role of brain protective agent is one of many brain protection treatment measures in a confusing and controversial topic, now on the following three aspects to talk about: 1 pathophysiology of brain protection therapy is well known that the presence of infarct tissue Ischemic penumbra is the basis of modern treatment of cerebral infarction, if the timely restoration of blood flow and improve