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目的探讨无创正压通气联合局部供氧对慢性阻塞性肺疾病(chronic obstructive pulmonarydisease,COPD)诱发的肢体溃疡的治疗效果。方法选择2008年1月—2012年3月治疗的COPD诱发的四肢溃疡患者40例,随机分为对照组和观察组各20例,对照组进行常规治疗,观察组给予无创正压通气加溃疡面局部供氧治疗。结果对照组总有效率60.0%,观察组总有效率100.0%,两组比较差异有统计学意义(P<0.05)。平均治疗时间对照组(39.94±15.01)d,观察组(27.35±13.48)d,两组比较差异有统计学意义(P<0.05)。结论对COPD诱发的肢体溃疡给予无创正压通气和溃疡面局部供氧治疗效果好,愈合时间短。
Objective To investigate the therapeutic effect of noninvasive positive pressure ventilation combined with local oxygen therapy on limb ulcers induced by chronic obstructive pulmonary disease (COPD). Methods Forty patients with COPD-induced limb ulcer were selected from January 2008 to March 2012. They were randomly divided into the control group and the observation group, with 20 cases in each group. The control group received routine treatment. The observation group received noninvasive positive pressure ventilation and ulcer surface Local oxygen therapy. Results The total effective rate was 60.0% in the control group and 100.0% in the observation group. The difference between the two groups was statistically significant (P <0.05). The mean treatment time was (39.94 ± 15.01) d in observation group and (27.35 ± 13.48) d in observation group, with significant difference between the two groups (P <0.05). Conclusion The non-invasive positive pressure ventilation and partial oxygen therapy of ulcer surface are effective for COPD-induced limb ulcers, and the healing time is short.