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分析了55例肝外胆管癌的病理特点和治疗方法及其与预后的关系。本组上段胆管癌占43.64%,中段胆管癌占21.82%,下段胆管癌34.55%,42例得到病理诊断,大体形态属浸润型24例、结节型6例、乳头型11例;镜下检查97.62%为腺癌,其中中高分化型51.22%。低分化型48.78%;上段胆管癌以浸润型、低分化腺癌居多.下段胆管癌以乳头型、中高分化腺癌为主。淋巴结转移45.24%,且多与胆管癌累及范围成正比,肝转移25.45%。手术切除11例(26.19%),其中上段胆管癌切除率11.76%,下段胆管癌切除率42.86%。平均生存期10.78±9.69月(x±SD)。从病理角度看,以下段胆管癌、浸润型低分化腺癌、伴淋巴结转移或肝转移者生存期明显缩短,治疗方面以手术切除组生存期(21.35±16.73月,X±SD)最长,胆肠内引流次之。并对肝外胆管癌的病程特点,不同治疗方法与预后的关系进行了探讨。
The pathological features and treatment of 55 cases of extrahepatic cholangiocarcinoma were analyzed and their relationship with prognosis was analyzed. The upper segment of the group accounted for 43.64% of the cholangiocarcinoma, 21.82% of the middle bile duct cancer, 34.55% of the lower bile duct cancer, and 42 cases were diagnosed pathologically. The gross morphology was invasive in 24 cases, nodular in 6 cases, papillary type In 11 cases, 97.62% of them were adenocarcinomas, of which 51.22% were moderately differentiated. Low-differentiation type 48.78%; the upper segment of bile duct cancer is mostly infiltrating, poorly differentiated adenocarcinoma. The lower segment of cholangiocarcinoma is mainly papillary and moderately differentiated adenocarcinoma. Lymph node metastasis was 45.24%, and was more than proportional to the extent of bile duct cancer involvement. Liver metastasis was 25.45%. Surgical resection was performed in 11 cases (26.19%). The resection rate of the upper segment was 11.76% and the resection rate of the lower segment was 42.86%. The average survival time was 10.78±9.69 months (x±SD). From the pathological point of view, the survival period of the following segments of cholangiocarcinoma, infiltrative poorly differentiated adenocarcinoma, lymph node metastasis or liver metastasis was significantly shortened, and the survival time in the surgical resection group was 21.35±16.73 months, X±SD. ) The longest, followed by drainage in the gall bladder. The characteristics of extrahepatic cholangiocarcinoma and the relationship between different treatment methods and prognosis were discussed.