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目的分析原发性十二指肠癌的诊断及临床治疗措施。方法回顾性分析南阳市第二人民医院2006年7月至2011年7月诊治的24例原发性十二指肠癌的临床资料。结果该病以中老年男性多见;病变部位以十二指肠降部多见;病理类型以腺癌居多;临床表现以上腹痛、腹胀及上腹部不适多见;内镜及双源CT检查阳性率较高;胰十二指肠切除术16例(66.7%),3年生存率为32.5%。结论①原发性十二指肠癌早期症状不典型、无特异性,预后差;②内镜、十二指肠低张造影及双源CT检查联合应用,可互为补充、取长补短、提高诊断准确率;③提高对该病的认识和警惕性,做到早期诊断、早期治疗,可以提高远期生存率、改善预后。
Objective To analyze the diagnosis and clinical treatment of primary duodenal cancer. Methods The clinical data of 24 cases of primary duodenal cancer diagnosed and treated in Nanyang Second People’s Hospital from July 2006 to July 2011 were retrospectively analyzed. Results The disease was more common in middle-aged and elderly men. The lesion was more common in descending part of the duodenum. The pathological type was mostly adenocarcinoma. The clinical manifestations were more common in abdominal pain, abdominal distension and upper abdominal discomfort. 16 cases (66.7%) had pancreatoduodenectomy, and the 3-year survival rate was 32.5%. Conclusion ① The early symptoms of primary duodenal cancer are not typical, non-specific, the prognosis is poor; ② endoscopic, duodenal low contrast angiography and dual-source CT combined application, can complement each other, learn from each other to improve diagnosis Accuracy; ③ improve awareness of the disease and vigilance, so early diagnosis and early treatment, can improve long-term survival and improve prognosis.