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我们应用ＡＢＣ免疫组织化学技术对３０６例活检的胃粘膜组织进行了ＣＥＡ含量的测定，结果显示：非萎缩性，萎缩性胃粘膜及胃癌组织中ＣＥＡ检出阳性率分别是７７．２２％，８６．４７％，９４．６８％。在非萎缩性胃粘膜，萎缩性胃粘膜及胃癌组织中都有一定的ＣＥＡ阳性显示率。ＣＥＡ对定性诊断意义不大，但在阳性强度表达上有明显差别（Ｐ＜０．０１），以胃癌明显。ＣＥＡ阳性强度等级相关分析也显示ＣＥＡ含量与胃癌及萎缩性胃炎病变程度是极明显的正相关（Ｒ＞０．７）。ＣＥＡ的测定对监测萎缩性胃炎的预后有一定价值。
We used ABC immunohistochemical technique to measure the CEA content of 306 biopsy gastric mucosal tissues. The results showed that the positive rate of CEA in non-atrophic, atrophic gastric mucosa and gastric cancer tissues was 77.22%, 86 respectively. .47%, 94.68%. In non-atrophic gastric mucosa, atrophic gastric mucosa and gastric cancer, there is a certain positive rate of CEA. CEA had little significance in qualitative diagnosis, but there was a significant difference in positive intensity expression (P<0.01). The correlation analysis of CEA positive intensity levels also showed that the CEA content was significantly positively correlated with the degree of gastric cancer and atrophic gastritis (R>0.7). The CEA assay has some value in monitoring the prognosis of atrophic gastritis.