患儿男性,10岁,学生,于1964年6月7日因左側上臂肿胀,皮肤起粟粒疹而就診。患儿于两天前由当地卫生院在左上臂三角肌处皮下注射流行性乙型脑炎組織培养疫苗1毫升(每5ml疫苗內加亚硫酸氢鈉液0.1ml以中和疫苗內之福尔馬林),次日局部开始紅肿,并出現較密集之粟粒样皮疹。当日清晨皮疹蔓延至左側上、下肢及躯干,自述痒甚,大小便及食欲正常,无头疼及头暈。统往史中,无过敏性疾患,并未注射过同种疫苗。体检:体溫37.5℃,脉搏110次/分,心肺及肝脾均未发現異常,左上臂明显肿胀,充血,触之热甚,自肩至肘部为密集之圓形粟粒样丘疹,肘窝最多,无水疱及脓疱,有搔痕,体表左側白头、面、頸、胸、腹、背、腰、臀,至下肢,足背及手背均有同样損害,唯远端丘疹較稀疏,屈側多于伸侧,損害仅限于 Male child, 10 years old, student, on June 7, 1964 due to swelling of the left upper arm, skin miliary eruption and treatment. Children in the local hospital two days ago in the left upper quadrant deltoid subcutaneous injection of Japanese encephalitis tissue culture vaccine 1 ml (5ml vaccine plus sodium bisulfite solution 0.1ml to neutralize the vaccine within the Forrester Marlin), the next day local redness began, and a more dense miliary rash. The rash spread to the left, lower extremities and trunk in the early morning of the day, itching, urine and normal appetite, no headache and dizziness. In the history of the past, no allergic diseases, not injected with the same vaccine. Physical examination: body temperature 37.5 ℃, pulse 110 beats / min, heart and lung and liver and spleen were found no abnormalities, the left upper arm was significantly swollen, congestion, heat even very, from shoulder to elbow for the dense circular miliary papules, cubital fossa Mostly, no blisters and pustules, scratches, body surface whitehead, face, neck, chest, abdomen, back, waist, buttocks, to the lower extremities, dorsal foot and back are the same damage, Flexing more than extensor side, damage is limited to