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对孕妇来说胎盘是一种不被排斥的异体移植物。在构成胎儿和母体解剖联系的胎盘或滋养叶细胞,是否存在着主要组织相容复合物已为人们所关注。已知正常胎盘有HLA抗原,滋养时细胞是否也有HLA,意见尚不一致。葡萄胎属异常胎盘,肉眼形态分两类:部分性和完全性,这为近代细胞遗传学所支持。完全性葡萄胎亚洲人的发病率约10倍于白种人;随着孕妇年龄的增加发病率增高,且易发展成绒癌,这些特点已引起妇产科医生的注意。完全性葡萄胎在形态学上是由增大的囊状绒毛组成,它充满宫腔而无胎儿、脐带或羊膜;在细胞遗传学方面,大多数具有正常女性核型。长期以来人们并不知道为什么出现这样不寻常的性分布,采
The placenta is a non-exclusive allograft for pregnant women. The existence of major histocompatibility complexes in the placenta or trophoblast cells that make up the fetus and maternal anatomy is of concern. It is known that there are HLA antigens in the normal placenta and whether the cells are HLA-positive when nourished. The opinions are not consistent. Hydatidiform mole is abnormal placenta, the naked eye morphology in two categories: partial and complete, which is supported by modern cytogenetics. The incidence of complete hydatidiform mole Asian people about 10 times the white; with the increase of the age of pregnant women increased incidence, and easy to develop into choriocarcinoma, these characteristics have attracted the attention of gynecologists. The complete mole is morphologically composed of an enlarged cystic villi that fills the uterus without the fetus, umbilical cord, or amniotic membrane, and in cytogenetics most have a normal female karyotype. For a long time, people did not know why such an unusual sex distribution occurred