[目的]讨论手术室的医院感染危险因素分析及管理对策。[方法]通过对手术室的医院感染危险因素的五点分析与五点管理对策进行对比和讨论。[结果]在平时的工作中,要加强无菌工作培训,也要对手术室的规章制度进行完善,对人员的管理进行监督。[结论]手术室的感染主要因素是医护人员没有做好消毒工作,应对管理最好的办法是提高医护人员的自我消毒意识。 [Objective] To discuss the risk factors of nosocomial infection in operating room and management strategies. [Methods] The five-point analysis of risk factors of nosocomial infection in operating room was compared with five management strategies. [Results] In the usual work, to strengthen the training of aseptic work, but also to improve the operating room rules and regulations, supervision of personnel management. [Conclusion] The main factor of infection in operating room is that medical staff do not do the disinfection work well. The best way to deal with management is to raise the self-disinfection consciousness of medical staff.