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分析了广东省1989～1993年报告的脊髓灰质炎（脊灰）疑似病例的口服脊灰疫苗（OPV）免疫状况和1994～1997年报告的急性弛缓性麻痹（AFP）病例的OPV免疫状况，以及部分AFP病例的血清中和抗体水平．1989～1993年报告的脊灰疑似病例中，服苗＜3次及OPV免疫史不详的占87.0％，每年有脊灰野病毒流行；1994～1997年报告的AFP病例中，服苗≥3次的占79．6％；采集了血清标本的AFP病例中，血清中和抗体阳性率达98．9％．4年间未发现脊灰野病毒引起的麻痹病例．此结果表明，维持高水平的人群全程免疫覆盖率可阻断脊灰野病毒的传播。
The oral poliovirus (OPV) immunization status of poliomyelitis (polio) suspected cases reported in Guangdong from 1989 to 1993 and OPV immunization status of acute flaccid paralysis (AFP) cases reported from 1994 to 1997 were analyzed, and Serum neutralizing antibody levels in some AFP cases. Among the suspected polio cases reported from 1989 to 1993, 87% of patients suspected of having OPV and unknown history of OPV were infected with poliovirus every year. Among AFP cases reported from 1994 to 1997, Accounting for 79.6%; serum samples collected AFP cases, serum neutralizing antibody positive rate of 98.9%. Four years, no paralysis caused by poliovirus was found. This result shows that the maintenance of high levels of population-wide immunization coverage can block the spread of poliovirus.