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目的探讨Wallenberg综合征(WS)的临床特点。方法对80例WS患者的临床资料进行分析研究。结果69例MRI阳性中66例患者为延髓梗塞所致,3例为延髓出血。患者多以眩晕、恶心、呕吐、吞咽困难、声嘶为主诉,急性起病并呈渐进性发展。除了典型的WS的症状外,还出现面瘫、肢体乏力(轻偏瘫)、复视、头痛、呃逆、面痛以及交叉性感觉障碍等症状和体征。头部磁共振成像(MRI)检查延髓病变阳性率为93.2%。结论延髓梗塞是WS的主要病因,但不是唯一原因。WS除了典型的症状和体征外,还具有非典型的临床特点。头部MRI的检查有助于WS的诊断。
Objective To investigate the clinical features of Wallenberg syndrome (WS). Methods The clinical data of 80 patients with WS were analyzed. Results Sixty-six of 69 cases with MRI positive were caused by obstruction of medulla oblongata and 3 cases with bulbar bullae. Patients with dizziness, nausea, vomiting, swallowing difficulties, hoarseness-based complaints, acute onset and progressive development. In addition to the symptoms of a typical WS, symptoms and signs such as facial paralysis, limb weakness (hemiparesis), diplopia, headache, hiccups, nausea, and cross-sensory disturbances also appear. Head MRI (posterior bulbar lesions) positive rate was 93.2%. Conclusions Lateral infarction is the main cause of WS, but not the only reason. In addition to the typical symptoms and signs, WS also has atypical clinical features. Head MRI examination contributes to the diagnosis of WS.