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博莱霉素常用于恶性肿瘤联合化疗之中。作者选择五例Ⅱ期睾丸癌患者,于一侧睾丸切除及腹部淋巴结清扫后,与长春新硷联合化疗,连续五天静脉注射博莱霉素30单位/天。在治疗前后进行了常规血液化验、各种凝血因子的检测、测定纤维蛋白元半衰期以及治疗前和治疗后七天骨髓活检。检查发现:治疗开始后第2～3天周围血小板及白细胞明显减少,血浆纤维蛋白元则随血小板减少而增加。其他数据无明显
Bleomycin is commonly used in combination chemotherapy for malignant tumors. The authors selected five cases of stage II testicular cancer patients, after one side of the testicular resection and abdomen lymph node dissection, combined with Changchun Xinyi chemotherapy, intravenous injection of bleomycin 30 units/day for five consecutive days. Routine blood tests, detection of various coagulation factors, determination of half-life of fibrinogen, and bone marrow biopsy before and after treatment were performed before and after treatment. It was found that platelets and white blood cells were significantly reduced around the 2nd to the 3rd day after the start of treatment, and plasma fibrinogens increased with the decrease of platelets. No other data is obvious