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流行性出血热疫苗效力检定采用国际标准毒株攻击，而国内生产的疫苗均采用国内地方毒株。为此，我们比较了不同毒株攻击对疫苗效力试验免疫动物血清中和抗体水平和疫苗合格率的影响。疫苗为1型（JR株）、五型（L99株）单价苗和1、巨型双价苗。效力试验分2针免疫法（0、14天免疫
Epidemiological hemorrhagic fever vaccine efficacy testing using international standard strain of attack, while the domestic production of vaccines are used domestic strains. To this end, we compared the effect of different strains of challenge on the level of serum neutralizing antibodies and the rate of vaccine compliance in immunized animals. The vaccine is type 1 (strain JR), type 5 (L99 strain), unit price and 1, giant bivalent vaccine. Efficacy test divided 2-needle immunization (0,14 days of immunization