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本文简述醛糖还原酶和多元醇通路与糖尿病慢性并发症的关系;对醛糖还原酶抑制剂治疗和预防糖尿病慢性并发症的作用进行评估,并介绍醛糖还原酶抑制剂的分类、研究进展、作用机理和副作用。
This article describes the relationship between aldose reductase and polyol pathways and chronic complications of diabetes mellitus; the role of aldose reductase inhibitors in the treatment and prevention of chronic complications of diabetes mellitus; and the classification of aldose reductase inhibitors Progress, mechanism of action and side effects.