脑缺血是细菌性脑膜炎(BM)常见并发症,是急性期高死亡率和高致残率的重要原因之一。作者用无创伤的TCD技术对22名(男12人.女10人)确诊的BM患者(16例致病菌已明确)进行前瞻性研究,以评估动脉狭窄程度以及与预后的关系。患者平均年龄48(18～85)岁,均于发病3d～7d内作首次TCD检查,并连续定期复查3次以上。 Cerebral ischemia is a common complication of bacterial meningitis (BM) and is one of the important causes of high mortality and morbidity in acute phase. The authors performed a prospective study of 22 patients (12 men and 10 women) diagnosed with BM (16 pathogenic bacteria have been identified) by non-invasive TCD technique to assess the degree of arterial stenosis and its relationship with prognosis. The average age of patients 48 (18 ~ 85) years old, were in the first 3 to 7 days of onset for the first time TCD examination, and continuous regular review of more than 3 times.