引言特别在最近5年间,已经报道了许多β-内酰胺酶类。对它们的物理-化学、微生物学及临床等方面做过多次评述。因此,使人们对β-内酰胺酶类的多种功能有了更多的了解,同时增加了药房在表面上看来似乎是不断涌现新的底物类和抑制剂类供应方面的独创性,这些新底物和抑制剂类仍然有相当多的新的内容须要加以评论,一些新的特性需要加以考虑。 INTRODUCTION Many beta-lactamases have been reported, especially in the last five years. Many reviews have been made on their physical-chemical, microbiological and clinical aspects. This has led to a greater understanding of the various functions of [beta] -lactamases and increased ingenuity in the pharmacy’s seemingly constant emergence of new substrate and inhibitor classes, There are still quite a few new things to consider for these new substrates and inhibitors, and some new features need to be considered.