氢质子磁共振波谱(1H-MRS)分析是一种检测体内组织、细胞生化代谢水平的无创性方法,它在颅内肿瘤的早期诊断、准确分期中有着重要价值。尤其是当一些因素(如合并有放射治疗后改变等)使常规磁共振成像诊断的准确性降低时,1H-MRS提供的代谢信息能提高对肿瘤残存和复发的诊断准确性,有待逐渐成为颅内占位性病变常规检查的一部分。该文对1H-MRS定量颅内肿瘤代谢物的方法及技术予以综述。 1H-MRS is a noninvasive method to detect tissue and cell biochemical metabolism in vivo. It has important value in the early diagnosis and accurate staging of intracranial tumors. In particular, the metabolic information provided by 1H-MRS can improve the diagnostic accuracy of residual tumor and recurrence when some factors (such as changes after combined with radiotherapy) reduce the accuracy of conventional MR imaging. Part of routine examination of occupying lesions. This article reviewed 1H-MRS quantitative methods and techniques of intracranial tumor metabolites.