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一叶获碱是大朝科植物一叶我叶中的主要生物碱,用于治疗麻痹症。喜树碱的生物作用归因于其内酯环,虽然该内酯环是否与一叶获碱的生物作用有关还不能肯定,但了解内酯环的水解过程有利于了解一叶该碱的化学特点。本文报道了一叶新碱内酯环的水解动力学,其水解过程可用下式表?
Alkaloids from one leaf are the main alkaloids in the leaves of the Dachaoaceae plant and are used for the treatment of paralysis. The biological action of camptothecin is attributed to its lactone ring. Although it is not certain whether the lactone ring is related to the biological action of a leaf, it is helpful to understand the hydrolysis process of the lactone ring to understand the chemistry of a leaf. Features. This article reports on the hydrolysis kinetics of a campolinolide ring, which can be hydrolyzed using the following formula: