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通过主动或被动免疫方法可复制出实验性自身免疫性重症肌无力(ＥＡＭＧ)动物模型,该模型在临床表现、药理学、电生理、免疫学及组织学表现等方面与ＭＧ病人很相似,因此,它是研究ＭＧ的极佳工具。本文从ＥＡＭＧ的动物选择、制备方法及检测指标等方面作一综述。
Animal models of experimental autoimmune myasthenia gravis (EAMG) can be replicated by either active or passive immunization and the model is similar to MG patients in terms of clinical presentation, pharmacology, electrophysiology, immunology and histological presentation , It is an excellent tool for studying MG. This article reviews the animal selection, preparation methods and testing indicators of EAMG.