论文部分内容阅读
用放射免疫法测定训练和非训练大鼠运动前、运动到５０％耐力时间（Ｔ１／２）和衰竭时丘脑下部和血浆β－内啡肽（β－ＥＰ）的含量，探索了训练与β－ＥＰ对急性运动反应的关系。结果表明：训练组大鼠丘脑下部β－ＥＰ含量在运动到Ｔ１／２和衰竭时分别较安静时提高了４％和１５％；对照组大鼠在Ｔ１／２时，β－ＥＰ的变化趋势同训练组，以后随运动生理负荷的增强而迅速降低，衰竭时较Ｔ１／２时降低了２６％，较训练组降低了３２％（Ｐ＜０．０５）。训练组大鼠血浆β－ＥＰ含量随运动开始迅速上升，Ｔ１／２时较运动前增加了５．７倍（Ｐ＜０．０１），以后上升的幅度减小；非训练组大鼠血浆β－ＥＰ也随运动开始迅速提高（Ｐ＜０．０１），Ｔ１／２后趋于稳定，在Ｔ１／２和衰竭时分别比训练组低２２％和２６％。表明非训练组大鼠丘脑下部β－Ｅｐ对急性运动呈明显的双相变化，训练提高了大鼠丘脑下部和血浆β－ＥＰ对衰竭运动的反应。
Radioimmunoassay was used to determine the contents of beta-endorphin (β-EP) in subthalamic and plasma before and after exercise to 50% endurance (T1 / 2) and failure in trained and non-trained rats. -EP on acute motor response. The results showed that the content of β-EP in the hypothalamus increased 4% and 15% respectively when exercising to T1 / 2 and failing in the training group, while the change tendency of β-EP in the control group at T1 / 2 Compared with the training group, the training group decreased rapidly with the increase of exercise physiology load, decreased by 26% at T1 / 2 and decreased by 32% (P <0.05) compared with training group. The content of β-EP in training group increased rapidly with the start of exercise, increased 5.7 times (P <0.01) at T1 / 2 and decreased later; while the level of plasma β -EP also increased rapidly with the onset of exercise (P <0.01), stabilized after T1 / 2, and decreased by 22% and 26% respectively at T1 / 2 and failure. The results showed that β-Ep in the hypothalamus of non-training group showed obvious biphasic changes to acute exercise, and training improved the response of rat hypothalamus and plasma β-EP to failure exercise.