多发性骨髓瘤（MM）是浆细胞异常增生的恶性肿瘤，异常浆细胞（即骨髓瘤细胞）浸润骨骼和软组织，产生M球蛋白，引起骨骼破坏、贫血、肾功能损害和免疫功能异常。部分MM患者会出现高钙血症，但对于其发生率有着不同的报道。现将1993－lop年8月确诊的刀例MM患者血钙改变分析如下 Multiple myeloma (MM) is a malignant tumor of abnormal proliferation of plasma cells. Abnormal plasma cells (myeloma cells) infiltrate bones and soft tissues and produce M-globulin, causing bone destruction, anemia, impaired renal function and abnormal immune function. Some MM patients develop hypercalcaemia, but there are different reports on their incidence. Now in August 1993-lop 8 cases of knife diagnosed in patients with calcium changes in calcium are as follows