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本文观察比较了博莱霉素A_5(国产)、博莱霉素A_2B_2(日本产)和博莱霉素A_2B_2国际标准品对于人胃癌细胞总DNA和其～50kb部分,以及人舌癌细胞总DNA的体外断链的时间和浓度效应。药物作用后的DNA经琼脂糖微型快速电泳和溴化乙锭(Ethidium Bromide)染色后在紫外光下观察并摄影。实验结果表明博莱霉素对人胃癌细胞总DNA和～50kb DNA以及人舌癌总DNA均有断
In this study, we compared the total DNA of human gastric cancer cells and their ~ 50kb parts with the bleomycin A_5 (domestic), bleomycin A_2B_2 (Japanese) and bleomycin A_2B_2 international standards, and the total DNA of human tongue cancer cells Time and concentration effect of chain scission in vitro. The drug-treated DNA was observed under ultraviolet light and photographed after it was stained with agarose micro-electrophoresis and Ethidium Bromide. The experimental results show that bleomycin on human gastric cancer cells total DNA and ~ 50kb DNA and human tongue cancer were total DNA were broken