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近年来子宫内膜癌的发病率有上升趋势，对内膜癌治疗方法的研究日益受到关注。雌激素过度刺激是内膜癌发病的重要因素，因此除传统的手术、放疗、化疗外，人们在寻找一种能拮抗雌激素作用的药物用于治疗内膜癌，孕激素疗法应运而生。该文系统地阐述了孕激素治疗子宫内膜癌的背景、临床应用、作用机理、病理变化、动物实验、用药方法及这些方面的进展。
In recent years, the incidence of endometrial cancer has an upward trend, the treatment of endometrial cancer research has drawn increasing attention. Estrogen over-stimulation is an important factor in the pathogenesis of endometrial cancer. Therefore, in addition to the traditional surgery, radiotherapy and chemotherapy, people are looking for a drug that can antagonize the effect of estrogen for the treatment of endometrial cancer. The progestin therapy has emerged. The article systematically expounded the background, clinical application, mechanism of action, pathological changes, animal experiments, methods of treatment and the progress of progesterone in the treatment of endometrial cancer.