以3-巯基丙酸(MPA)为稳定剂,利用水相合成法合成具有独特光学性质的Mn掺杂Zn S量子点(QDs),基于该量子点的室温磷光性质建立了一种高效、灵敏的检测抗癌药物顺铂(cisplatin,DDP)的新方法。该量子点在室温不除氧的条件下即可发射较强的磷光信号。在p H=7.4的磷酸盐缓冲液中,顺铂作为良好的电子受体,能够通过光诱导电子转移(PIET)原理猝灭Mn掺杂Zn S量子点的室温磷光(RTP)。在最优实验条件下,该方法的线性范围为2.5~50μmol/L,相关系数R=0.99,检出限为0.85μmol/L。 Mn-doped ZnS quantum dots (QDs) with unique optical properties were synthesized by aqueous phase synthesis using 3-mercaptopropionic acid (MPA) as a stabilizer. Based on the room-temperature phosphorescence properties of the quantum dots, an efficient and sensitive A new method to detect anticancer drug cisplatin (DDP). The quantum dot emits a strong phosphorescent signal at room temperature without deoxygenation. Cisplatin, as a good electron acceptor, can quench room temperature phosphorescence (RTP) of Mn-doped ZnS QDs by the principle of photoinduced electron transfer (PIET) in phosphate buffer with pH 7.4. Under the optimal experimental conditions, the linear range of this method was 2.5-50 μmol / L with a correlation coefficient of 0.99 and a detection limit of 0.85 μmol / L.