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目的探讨酒精中毒性肝硬化(ALC)的临床特征。提高诊治水平,降低死亡率。方法回顾分析我院2003年1月至2011年12月收治的247例ALC临床资料。结果 ALC247例中男244例,女3例。其中纳差、乏力149例,腹胀182例,黄疸61例,腹水134例,上消化道出血95例,肝性脑病38例,肝癌20例,糖尿病26例,感染38例。经对症支持治疗后,好转191例,放弃24例,死亡32例。结论 247例ALC患者中男性占多数,肝肿大占1/2,含并胃炎、胃溃疡。肝功能以AST、γ-GT升高为主,AST/ALT≥2。ALC死亡原因是上消化道出血,肝性脑病及严重感染。
Objective To investigate the clinical features of alcoholic cirrhosis (ALC). Improve diagnosis and treatment, reduce mortality. Methods A retrospective analysis of our hospital from January 2003 to December 2011 admitted 247 cases of ALC clinical data. Results ALC247 cases, 244 cases of male and 3 females. Among them, there were 149 cases of anorexia, 144 cases of abdominal distension, 61 cases of jaundice, 134 cases of ascites, 95 cases of upper gastrointestinal bleeding, 38 cases of hepatic encephalopathy, 20 cases of liver cancer, 26 cases of diabetes and 38 cases of infection. After symptomatic and supportive treatment, 191 cases were improved, 24 cases were given up and 32 cases died. Conclusions The majority of 247 ALC patients are male, with hepatomegaly accounting for 1/2, including gastritis and gastric ulcer. Liver function in AST, γ-GT increased mainly AST / ALT ≥ 2. The causes of death in ALC are upper gastrointestinal bleeding, hepatic encephalopathy and severe infections.