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本文对胃炎、胃粘膜管状异型增生及弥漫型胃癌采用过氧化物酶联链菌素亲生物蛋白（Ｓ—Ｐ）方法进行了ｋｉ—６７及ＣＥＡ的免疫组织化学研究，发现ｋｉ—６７及ＣＥＡ的阳性表达率在胃炎管状异型增生及弥漫型胃癌中呈明显递增趋势。提示管状异型增生可能是弥漫型胃癌的发病过程中重要的过渡阶段。
In this paper, the immunohistochemical study of ki-67 and CEA was performed on the gastritis, gastric mucosal tubular dysplasia and diffuse gastric cancer using the peroxidase-streptavidin pro-bio-protein (S-P) method. Ki-67 and CEA were found. The positive expression rate of gastric cancer in gastric dysplasia and diffuse gastric cancer showed an increasing trend. It is suggested that tubular dysplasia may be an important transitional stage in the pathogenesis of diffuse gastric cancer.