药物性血小板减少症并非少见,本病常以皮肤粘膜弥漫性出血为主要表现,有时可因颅内或胄肠道出血导致死亡。而本病引起致死性肺内出血则为罕见,作者遇到1例。该例为女性71岁,因肩痛服羟保泰松100mg发生弥漫性淤斑入院。既往曾服羟保泰松2年余。体检:血压180/100mmHg,脉博96次/分,右第二肋间闻及Ⅲ级全收缩期杂音,向颈传导,肺部无异常。眼底见视网膜散在性淤点。实验室资料:血色素12gm%,白细胞5300/mm~8,分类正常。血小板2万/mm~3,凝血酶元等正常。心电图提示心动过速与左室肥大劳损,胸片正常。骨髓象中巨核细胞减少。入院后给予强的松(60mg/日),反复输入血小板,但血小板仍2万/mm~3。入院第15天突然左胸痛,向背放射伴气急、不安、苍白、肢冷和出汗。血压130/70mmHg,脉 Drug-induced thrombocytopenia is not uncommon, the disease often diffuse mucocutaneous bleeding as the main performance, sometimes due to intracranial or intestinal bleeding caused by death. The disease caused by fatal pulmonary hemorrhage is rare, the author encountered 1 case. The case of a woman 71 years old, due to shoulder pain metoprolol 100mg diffuse ecchymosis hospitalized. Previously served hydroxybiturate more than 2 years. Physical examination: blood pressure 180 / 100mmHg, pulse Bo 96 times / min, right second intercostal smell and Ⅲ grade systolic murmur, conduction to the neck, no abnormality in the lungs. Fundus see the eyes scattered scattered bruises. Laboratory data: hemoglobin 12gm%, white blood cells 5300 / mm ~ 8, normal classification. Platelets 20,000 / mm ~ 3, thrombin and other normal. ECG prompts tachycardia and left ventricular hypertrophy strain, chest X-ray normal. Myeloid megakaryocytic reduction. After admission to give prednisone (60mg / day), repeated input of platelets, but the platelet is still 20,000 / mm ~ 3. Sudden left chest pain on the 15th day of hospital admission, back to radiation with urgency, anxiety, pale, cold and sweating. Blood pressure 130 / 70mmHg, pulse