对象和方法1　研究对象　选自本院门诊围绝经期骨质疏松妇女 2 0例 ,平均年龄 48.6( 4 3～ 5 4 )岁 ,围绝经期正常妇女 2 0例 ,平均年龄 49.3( 4 2～ 5 2 )岁 ,以上病例均排除甲状腺机能亢进、肾功能不全等疾病 ,同时排除服用影响骨代谢药物史。2　研究方法　血清 Ca2 +、P3-测 Subjects and Methods 1 The subjects were selected from 20 outpatients with perimenopausal osteoporosis who had an average age of 48.6 (43-54) years and 20 peri-menopausal women with an average age of 49.3 (42 ~ 5 2) years old, the above cases were excluded hyperthyroidism, renal insufficiency and other diseases, while excluding the use of drugs that affect the history of bone metabolism. 2 research methods serum Ca2 +, P3-measured