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[目的]了解广州铁路地区不同职业人员乙型肝炎病毒(HBV)感染状况及感染模式,为制定有效的防治对策和措施提供科学依据。[方法]对2006~2007年在广州铁路疾病预防控制中心参加职业体检人员HBV感染指标和肝功能检测资料进行分析。[结果]2年合计检测2 837人,HBsAg阳性率为10.43%,丙氨酸氨基转移酶升高率为1.97%。HBsAg阳性率,2006年为10.14%,2007年为10.65%(P>0.05);铁路沿线职工为12.09%,机关办公室人员为6.74%(P<0.01);广梅汕地区为10.03%,深圳地区为12.71%,广州地区为9.02%(P<0.05)。HBsAg阳性的296例中,HBsAg、HBeAg、抗-HBc阳性的占12.84%,HBsAg、抗-HBe、抗-HBc阳性的占62.16%,HBsAg、抗-HBc阳性的占22.30%,其他5种感染类型的占2.70%。[结论]铁路沿线基层工人HBsAg阳性率较高。
[Objective] To understand the status of hepatitis B virus (HBV) infection and infection patterns of different occupations in Guangzhou railway area and provide a scientific basis for formulating effective prevention and control measures and measures. [Methods] The data of HBV infection and liver function test in occupational medical personnel from 2006 to 2007 in Guangzhou Railway Disease Prevention and Control Center were analyzed. [Results] A total of 2 837 persons were tested in 2 years, the positive rate of HBsAg was 10.43%, and the increase rate of alanine aminotransferase was 1.97%. The positive rate of HBsAg was 10.14% in 2006 and 10.65% in 2007 (P> 0.05). The number of workers along the railway line was 12.09% and the office staff was 6.74% (P <0.01), that of Guangmeishan area was 10.03% Was 12.71% in Guangzhou and 9.02% in Guangzhou (P <0.05). Among 296 HBsAg positive cases, HBsAg, HBeAg and anti-HBc accounted for 12.84%, HBsAg, anti-HBe and anti-HBc accounted for 62.16%, HBsAg and anti-HBc accounted for 22.30%, and other five infections Type accounted for 2.70%. [Conclusion] The positive rate of HBsAg among grassroots workers along the railway line is high.