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目的 :观察乌拉地尔治疗急性左心室衰竭的临床疗效。方法 :42例左心室衰竭患者 ,予以乌拉地尔 12 .5～ 2 5mg稀释于 10ml生理盐水中静注 ,根据血压情况 ,必要时于 10min后再次静注 12 .5～ 2 5mg ,然后以 5 0mg乌拉地尔加于 2 5 0ml液体中静滴 ,10 0～ 40 0 μg·min-1,所有患者未同时使用其他扩血管药物。结果 :乌拉地尔可显著降低急性左心室衰竭患者的收缩压、舒张压、心率及收缩压心率乘积 ,升高动脉血氧分压。用药后 5～ 10min困难症状即有缓解 ,双肺湿罗音及紫绀逐渐减少至消失。结论 :乌拉地尔治疗各种原因引起的急性左心室衰竭 ,可有效改善患者的临床症状及血流动力学指标。
Objective: To observe the clinical efficacy of urapidil in the treatment of acute left ventricular failure. Methods: Forty-two patients with left ventricular failure were treated with urapidil 12.5 ~ 25mg diluted in 10ml normal saline. According to the blood pressure, if necessary, they were intravenously injected with 12.5 ~ 25mg once again after 10min. 0mg urapidil plus 250ml liquid intravenous infusion, 100 ~ 40 0 μg · min-1, all patients did not use other vasodilator drugs. Results: Urapidil could significantly reduce the systolic blood pressure, diastolic blood pressure, heart rate and systolic pressure heart rate in patients with acute left ventricular failure and increase the arterial oxygen pressure. 5 ~ 10min after treatment symptoms that have relief, lung wet rales and cyanosis gradually reduced to disappear. Conclusion: Urapidil treats various causes of acute left ventricular failure, which can effectively improve the clinical symptoms and hemodynamic parameters.