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近年研究认为,高同型半胱氨酸血症(HHcy)是动脉硬化的一个独立危险因子;而体内的同型半胱氨酸(Hcy)来源于食物中的蛋氨酸,过量摄入蛋氨酸可诱发HHcy。2007年6~12月我们通过予兔高蛋氨酸饮食复制HHcy动物模型,以观察与动脉粥样硬化相关指标的变化,同时观察辛伐他汀对Hhcy的干预?
Recent studies suggest that homocysteine (HHcy) is an independent risk factor for atherosclerosis. In vivo homocysteine (Hcy) is derived from methionine in food and excessive intake of methionine can induce HHcy. From June to December 2007, we replicated animal model of HHcy by high-methionine diet to observe the changes of the indexes related to atherosclerosis, and observed the intervention of simvastatin on Hhcy.