目的:优化驱虫斑鸠菊水提取液的澄清工艺。方法:采用正交试验设计,以浸膏量、浸膏中紫铆素和总黄酮含量为评分指标,筛选驱虫斑鸠菊水提取液的澄清条件。结果:驱虫斑鸠菊水提取液的澄清条件为:ZTC1+1型澄清剂的加入顺序为先加入0.5%(g.mL-1)澄清剂B溶液,再加入1.0%(g.mL-1)澄清剂A溶液;澄清剂B和A的最佳用量分别为2.0%(V/V)和0.5%(V/V);反应温度分别为(80±1)℃和(60±1)℃;反应时间均为2h。结论:该工艺简便、可行,可为实际生产提供理论依据。 Objective: To optimize the clarification process of aqueous extract of Vernonia lutea. Methods: Orthogonal design was used to extract the amount of extract, extract purple rile and total flavonoids as a scoring index, screening the deworming Vernonia aqueous extract clarification conditions. Results: The conditions for the clarification of aqueous extract of Vernonia lutea were as follows: the addition of 0.5% (g.mL-1) Clarifier B to ZTC1 + 1 clarifier followed by 1.0% (g.mL-1) The best dosage of clarifying agent B and A were 2.0% (V / V) and 0.5% (V / V) respectively; the reaction temperature was (80 ± 1) ℃ and (60 ± 1) ℃; The reaction time is 2h. Conclusion: The process is simple and feasible, which can provide theoretical basis for actual production.