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甲胎蛋白简介甲胎蛋白(Alpha-Fetoprotein,AFP)主要由胚胎的肝细胞及卵黄囊细胞合成,但胎儿的肠细胞也可合成少量。人类AFP的分子量为70,000,由一种简单的多肽链所组成。分娩时AFP合成即停止,但可从脐带血及新生儿的血液中测得此种物质,浓度约为10～50微克/毫升,其半衰期约为3～5天。在正常成人血清中亦存在微量AFP,约为1～17毫微克/毫升。目前检查AFP的的方法有:放射免疫测定、对流免疫电泳、免疫琼脂扩散等,其中灵敏度最
Alpha-Fetoprotein Introduction Alpha-Fetoprotein (AFP) is mainly synthesized by the embryonic liver cells and yolk sac cells, but fetal intestinal cells can also be synthesized in small amounts. Human AFP has a molecular weight of 70,000 and consists of a simple polypeptide chain. AFP synthesis during childbirth stopped, but the cord blood and neonatal blood can be measured in the substance, the concentration of about 10 ~ 50 micrograms / ml, the half-life of about 3 to 5 days. Trace amounts of AFP also exist in normal adult serum, ranging from about 1 to 17 ng / mL. The current method of checking AFP are: radioimmunoassay, convection immune electrophoresis, immunological agar diffusion, etc., of which the most sensitive